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CGRPβ suppresses the pathogenesis of ulcerative colitis via the immunoproteasome

Abstract Various factors have been implicated in the pathogenesis of ulcerative colitis (UC), with immune system failure being the most important one. Calcitonin gene-related peptide (CGRP), a neuropeptide with two isoforms, CGRPα and CGRPβ, has been reported to regulate the immune system. In this s...

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Principais autores: Tatsuya Shibao, Hiroaki Hase, Kodai Mizokami, Atsushi Usui, Kaori Kitae, Yuko Ueda, Kentaro Jingushi, Kazutake Tsujikawa
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Acceso en liña:https://doi.org/10.1038/s41598-025-91933-w
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