Lipidomics reveals the reshaping of the mitochondrial phospholipid profile in cells lacking OPA1 and mitofusins

Depletion or mutations of key proteins for mitochondrial fusion, like optic atrophy 1 (OPA1) and mitofusins 1 and 2 (Mfn 1 and 2), are known to significantly impact the mitochondrial ultrastructure, suggesting alterations of their membranes’ lipid profiles. In order to make an insight into this issu...

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Detalhes bibliográficos

Principais autores:	Andrea Castellaneta, Ilario Losito, Vito Porcelli, Serena Barile, Alessandra Maresca, Valentina Del Dotto, Valentina Losacco, Ludovica Sofia Guadalupi, Cosima Damiana Calvano, David C. Chan, Valerio Carelli, Luigi Palmieri, Tommaso R.I. Cataldi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-06-01
coleção:	Journal of Lipid Research
Assuntos:	glycerophospholipids lipidomics mitochondria phospholipids phospholipids/biosynthesis OPA1
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227524000683
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