Design and synthesis of a novel curcumin–combretastatin A4 molecular skeleton: two pharmacophores†
The logical design and synthesis of a novel compound combretastatin A-4-integrated curcumin is presented. Claisen condensation of phenylacetone with ethyl acetates formed 1,5-diphenylpentane-2,4-dione. Condensation of the dione with benzaldehyde via a modified Pabon procedure formed combretastatin A...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Royal Society of Chemistry
2024-11-01
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| Seri Bilgileri: | RSC Advances |
| Online Erişim: | https://pubs.rsc.org/ra/article-pdf/14/50/37227/10002570/d4ra06618a.pdf |
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