Comparative Structural Modeling Suggests Distinct Signatures of Conformational Plasticity and Surface Physicochemistry in Phytoene Synthase and Dehydrosqualene Synthase

Carotenoids are essential metabolites involved in photosynthesis, cellular protection, pigmentation, and antioxidant activities. Phytoene synthase (PSY/CrtB) utilizes C20 substrates in carotenoid biosynthesis, whereas its structural homolog, dehydrosqualene synthase (CrtM), preferentially accepts C1...

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Detalhes bibliográficos

Principais autores:	Ade Rizqi Ridwan Firdaus, Muhammad Yusuf, Shun Tamaki, Keiichi Mochida, Toto Subroto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-06-01
Colecção:	Molecules
Assuntos:	phytoene synthase dehydrosqualene synthase carotenoid biosynthesis molecular dynamics
Acesso em linha:	https://www.mdpi.com/1420-3049/31/12/1995
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