Comparative Structural Modeling Suggests Distinct Signatures of Conformational Plasticity and Surface Physicochemistry in Phytoene Synthase and Dehydrosqualene Synthase

Carotenoids are essential metabolites involved in photosynthesis, cellular protection, pigmentation, and antioxidant activities. Phytoene synthase (PSY/CrtB) utilizes C20 substrates in carotenoid biosynthesis, whereas its structural homolog, dehydrosqualene synthase (CrtM), preferentially accepts C1...

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Bibliografische Detailangaben

Hauptverfasser:	Ade Rizqi Ridwan Firdaus, Muhammad Yusuf, Shun Tamaki, Keiichi Mochida, Toto Subroto
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-06-01
Schriftenreihe:	Molecules
Schlagworte:	phytoene synthase dehydrosqualene synthase carotenoid biosynthesis molecular dynamics
Online-Zugang:	https://www.mdpi.com/1420-3049/31/12/1995
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