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T-Cell Gene Therapy in Cancer Immunotherapy: Why It Is No Longer Just CARs on The Road

T-cells have a natural ability to fight cancer cells in the tumour microenvironment. Due to thymic selection and tissue-driven immunomodulation, these cancer-fighting T-cells are generally low in number and exhausted. One way to overcome these issues is to genetically alter T-cells to improve their...

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Autors principals: Michael D. Crowther, Inge Marie Svane, Özcan Met
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2020-06-01
Col·lecció:Cells
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Accés en línia:https://www.mdpi.com/2073-4409/9/7/1588
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