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Bone marrow-derived cPLA2α contributes to renal fibrosis progression

The group IVA calcium-dependent cytosolic phospholipase A2 (cPLA2α) enzyme directs a complex “eicosanoid storm” that accompanies the tissue response to injury. cPLA2α and its downstream eicosanoid mediators are also implicated in the pathogenesis of fibrosis in many organs, including the kidney. We...

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Furkejuvvon:
Váldodahkkit: John R. Montford, Allison M.B. Lehman, Colin D. Bauer, Jelena Klawitter, Jost Klawitter, Joanna M. Poczobutt, Micah Scobey, Mary Weiser-Evans, Raphael A. Nemenoff, Seth B. Furgeson
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2018-02-01
Ráidu:Journal of Lipid Research
Fáttát:
eicosanoids
extracellular matrix
kidney
inflammation
lipidomics
phospholipases/A2
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S0022227520342401
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