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High-Throughput Screening for the Prevalence of Neutralizing Antibodies against Human Adenovirus Serotype 5

Adenoviral vectors based on the human adenovirus species C serotype 5 (HAdV-C5) are commonly used for vector-based gene therapies and vaccines. In the preclinical stages of development, their safety and efficacy are often validated in suitable animal models. However, pre-existing neutralizing antibo...

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Bibliografische gegevens
Hoofdauteurs: Jochen M. Wettengel, Hiroaki Naka, Gregory A. Dissen, Jeffrey Torgerson, Michelle Pounder, Simon F. Mueller, Elisabeth Mueller, Philipp Hagen, Micah Brandt, Ulrike Protzer, Benjamin J. Burwitz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2024-02-01
Reeks:Vaccines
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Online toegang:https://www.mdpi.com/2076-393X/12/2/155
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