High-Throughput Screening for the Prevalence of Neutralizing Antibodies against Human Adenovirus Serotype 5

Adenoviral vectors based on the human adenovirus species C serotype 5 (HAdV-C5) are commonly used for vector-based gene therapies and vaccines. In the preclinical stages of development, their safety and efficacy are often validated in suitable animal models. However, pre-existing neutralizing antibo...

Description complète

Détails bibliographiques

Auteurs principaux:	Jochen M. Wettengel, Hiroaki Naka, Gregory A. Dissen, Jeffrey Torgerson, Michelle Pounder, Simon F. Mueller, Elisabeth Mueller, Philipp Hagen, Micah Brandt, Ulrike Protzer, Benjamin J. Burwitz
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2024-02-01
Collection:	Vaccines
Sujets:	adenoviral vector adenoviral vaccine adenoviral immunity neutralizing antibodies
Accès en ligne:	https://www.mdpi.com/2076-393X/12/2/155
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!