2′, 5′-Oligoadenylate Synthetase 2 (OAS2) Inhibits Zika Virus Replication through Activation of Type Ι IFN Signaling Pathway

Background: 2′, 5′-oligoadenylate synthetase 2 (OAS2) has been known as an antiviral interferon-stimulated gene (ISG). However, the role of OAS2 on Zika virus (ZIKV) replication is still unknown. In this study, we sought to explore the effect of OAS2 on ZIKV replication and its underlying mechanism....

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Detalles Bibliográficos

Principais autores:	Xinzhong Liao, He Xie, Shilin Li, Haiyan Ye, Shuang Li, Kai Ren, Yujia Li, Min Xu, Wenyu Lin, Xiaoqiong Duan, Chunhui Yang, Limin Chen
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2020-04-01
Series:	Viruses
Assuntos:	OAS2 ZIKV replication IFNβ Jak/STAT signaling pathway
Acceso en liña:	https://www.mdpi.com/1999-4915/12/4/418
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