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Antimicrobial Peptide K11 Selectively Recognizes Bacterial Biomimetic Membranes and Acts by Twisting Their Bilayers

K11 is a synthetic peptide originating from the introduction of a lysine residue in position 11 within the sequence of a rationally designed antibacterial scaffold. Despite its remarkable antibacterial properties towards many ESKAPE bacteria and its optimal therapeutic index (320), a detailed descri...

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Principais autores: Francisco Ramos-Martín, Claudia Herrera-León, Viviane Antonietti, Pascal Sonnet, Catherine Sarazin, Nicola D’Amelio
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-12-01
Serier:Pharmaceuticals
Fag:
antimicrobial peptide
biomembranes
ESKAPE
antibiotic resistance
NMR
molecular dynamics
Online adgang:https://www.mdpi.com/1424-8247/14/1/1
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