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Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway

Background: Neuronal cholesterol deficiency may contribute to the synaptopathy observed in Alzheimer’s disease (AD). However, the underlying mechanisms remain poorly understood. Intact synaptic vesicle (SV) mobility is crucial for normal synaptic function, whereas disrupted SV mob...

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Bibliografische gegevens
Hoofdauteurs: Atikam Qurban, Mengqi Zhang, Hengbing Zu, Kai Yao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: IMR Press 2025-01-01
Reeks:Frontiers in Bioscience-Landmark
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Online toegang:https://www.imrpress.com/journal/FBL/30/1/10.31083/FBL27111
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