Radiotherapy combined with docetaxel alters the immune phenotype of HNSCC cells and results in increased surface expression of CD137 and release of HMGB1 of specifically HPV-positive tumor cells

Purpose: Human papilloma virus (HPV) positive head and neck squamous cell carcinoma (HNSCC) tumors respond significantly better to anticancer treatments. It is assumed to be due to a better response to radiotherapy (RT), and presumably to an increased immunogenicity. However, little is known how the...

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Библиографические подробности

Главные авторы:	Fridolin Grottker, Simon Gehre, Clara M. Reichardt, Azzaya Sengedorj, Tina Jost, Thorsten Rieckmann, Markus Hecht, Antoniu-Oreste Gostian, Benjamin Frey, Rainer Fietkau, Udo S. Gaipl, Michael Rückert
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2023-11-01
Серии:	Neoplasia: An International Journal for Oncology Research
Предметы:	Radiotherapy Docetaxel Head and neck squamous cell carcinoma HPV status Immune checkpoint molecules HMGB1
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S1476558623000684
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