Spectra without stories: reporting 94% dark and unidentified ancient proteomes [version 1; peer review: 2 approved, 1 approved with reservations]
Background Data-dependent, bottom-up proteomics is widely used for identifying proteins and peptides. However, one key challenge is that 70% of fragment ion spectra consistently fail to be assigned by conventional database searching. This ‘dark matter’ of bottom-up proteomics seems to affect fields...
Kaydedildi:
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
F1000 Research Ltd
2024-04-01
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| Seri Bilgileri: | Open Research Europe |
| Konular: | |
| Online Erişim: | https://open-research-europe.ec.europa.eu/articles/4-71/v1 |
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