Antitumor Activity of Nanoparticles Loaded with PHT-427, a Novel AKT/PDK1 Inhibitor, for the Treatment of Head and Neck Squamous Cell Carcinoma

Currently, new treatments are required to supplement the current standard of care for head and neck squamous cell carcinoma (HNSCC). The phosphatidylinositol3-kinase (PI3K) signaling pathway is commonly altered and activated in HNSCC. PHT-427 is a dual PI3K-mammalian target of the AKT/PDK1 inhibitor...

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Principais autores:	Joaquín Yanes-Díaz, Raquel Palao-Suay, María Rosa Aguilar, Juan Ignacio Riestra-Ayora, Antonio Ferruelo-Alonso, Luis Rojo del Olmo, Blanca Vázquez-Lasa, Ricardo Sanz-Fernández, Carolina Sánchez-Rodríguez
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2021-08-01
סדרה:	Pharmaceutics
נושאים:	PHT-427 inhibitor polymeric nanoparticle PI3K pathway AKT PDK1 hypopharynx carcinoma squamous cells
גישה מקוונת:	https://www.mdpi.com/1999-4923/13/8/1242
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!