क्यूआर कोड

Antitumor Activity of Nanoparticles Loaded with PHT-427, a Novel AKT/PDK1 Inhibitor, for the Treatment of Head and Neck Squamous Cell Carcinoma

Currently, new treatments are required to supplement the current standard of care for head and neck squamous cell carcinoma (HNSCC). The phosphatidylinositol3-kinase (PI3K) signaling pathway is commonly altered and activated in HNSCC. PHT-427 is a dual PI3K-mammalian target of the AKT/PDK1 inhibitor...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Joaquín Yanes-Díaz, Raquel Palao-Suay, María Rosa Aguilar, Juan Ignacio Riestra-Ayora, Antonio Ferruelo-Alonso, Luis Rojo del Olmo, Blanca Vázquez-Lasa, Ricardo Sanz-Fernández, Carolina Sánchez-Rodríguez
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2021-08-01
श्रृंखला:Pharmaceutics
विषय:
PHT-427 inhibitor
polymeric nanoparticle
PI3K pathway
AKT
PDK1
hypopharynx carcinoma squamous cells
ऑनलाइन पहुंच:https://www.mdpi.com/1999-4923/13/8/1242
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