PKR-mediated stress response enhances dengue and Zika virus replication

ABSTRACT The mechanisms by which flaviviruses use non-canonical translation to support their replication in host cells are largely unknown. Here, we investigated how the integrated stress response (ISR), which promotes translational arrest by eIF2ɑ phosphorylation (p-eIF2ɑ), regulates flavivirus rep...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Taissa Ricciardi-Jorge, Edroaldo Lummertz da Rocha, Edgar Gonzalez-Kozlova, Gabriela Flavia Rodrigues-Luiz, Brian J. Ferguson, Trevor Sweeney, Nerea Irigoyen, Daniel Santos Mansur
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology 2023-10-01
סדרה:	mBio
נושאים:	dengue virus Zika virus innate immunity protein translation PKR
גישה מקוונת:	https://journals.asm.org/doi/10.1128/mbio.00934-23
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!