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Pro-Inflammatory Cytokines Predict Relapse-Free Survival after One Month of Interferon-α but Not Observation in Intermediate Risk Melanoma Patients.

E1697 was a phase III trial of adjuvant interferon (IFN)-α2b for one month (Arm B) versus observation (Arm A) in patients with resected melanoma at intermediate risk. We evaluated the levels of candidate serum cytokines, the HLA genotype, polymorphisms of CTLA4 and FOXP3 genes and the development of...

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Detalhes bibliográficos
Principais autores: Ahmad A Tarhini, Yan Lin, Haris Zahoor, Yongli Shuai, Lisa H Butterfield, Steven Ringquist, Helen Gogas, Cindy Sander, Sandra Lee, Sanjiv S Agarwala, John M Kirwood
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4508028?pdf=render
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