High protein copy number is required to suppress stochasticity in the cyanobacterial circadian clock

Circadian clocks must maintain their fidelity despite stochasticity arising from finite protein copy numbers. Here, the authors show that a small cyanobacterium relies on an environmentally driven timer likely because its low protein copy numbers cannot support an accurate free-running clock.

Detalhes bibliográficos

Principais autores:	Justin Chew, Eugene Leypunskiy, Jenny Lin, Arvind Murugan, Michael J. Rust
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2018-08-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-018-05109-4
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