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Large-Scale de novo Oligonucleotide Synthesis for Whole-Genome Synthesis and Data Storage: Challenges and Opportunities

Over the past decades, remarkable progress on phosphoramidite chemistry-based large-scale de novo oligonucleotide synthesis has been achieved, enabling numerous novel and exciting applications. Among them, de novo genome synthesis and DNA data storage are striking. However, to make these two applica...

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Hauptverfasser: Li-Fu Song, Zheng-Hua Deng, Zi-Yi Gong, Lu-Lu Li, Bing-Zhi Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-06-01
Schriftenreihe:Frontiers in Bioengineering and Biotechnology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fbioe.2021.689797/full
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