Large-Scale de novo Oligonucleotide Synthesis for Whole-Genome Synthesis and Data Storage: Challenges and Opportunities

Over the past decades, remarkable progress on phosphoramidite chemistry-based large-scale de novo oligonucleotide synthesis has been achieved, enabling numerous novel and exciting applications. Among them, de novo genome synthesis and DNA data storage are striking. However, to make these two applica...

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Autori principali:	Li-Fu Song, Zheng-Hua Deng, Zi-Yi Gong, Lu-Lu Li, Bing-Zhi Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-06-01
Serie:	Frontiers in Bioengineering and Biotechnology
Soggetti:	oligonucleotide synthesis DNA synthesis synthetic biology whole-genome synthesis data storage in DNA DNA-based data storage
Accesso online:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.689797/full
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