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PLX3397 attenuated tumor growth and remodeled tumor microenvironment of recurrent glioblastoma

Abstract The tumor microenvironment (TME) is critically implicated in glioblastoma (GBM) recurrence, therapeutic resistance, and immune evasion. By analyzing both primary and recurrent GBM from Chinese Glioma Genome Atlas (CGGA) and clinical samples, we identified significant differences in TME. To...

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Bibliografische gegevens
Hoofdauteurs: Chen Yang, Linzhi Cai, Xi Xiang, Xiwei Zhu, Chengli Liu, Jianming Liao, Zhan Zhang, Mingchang Li
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2025-12-01
Reeks:Scientific Reports
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Online toegang:https://doi.org/10.1038/s41598-025-32943-6
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