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Both STING and MAVS fish orthologs contribute to the induction of interferon mediated by RIG-I.

Viral infections are detected in most cases by the host innate immune system through pattern-recognition receptors (PRR), the sensors for pathogen-associated molecular patterns (PAMPs), which induce the production of cytokines, such as type I interferons (IFN). Recent identification in mammalian and...

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Bibliografiske detaljer
Principais autores: Stéphane Biacchesi, Emilie Mérour, Annie Lamoureux, Julie Bernard, Michel Brémont
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0047737&type=printable
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