Ramucirumab induces apoptosis in Caco-2 cells via mitochondrial impairment and caspase activation
Abstract Ramucirumab, a monoclonal antibody that targets vascular endothelial growth factor receptor-2 (VEGFR-2), is primarily known for its ability to inhibit angiogenesis in a variety of cancer types. Its direct cytotoxic mechanisms in colorectal cancer cells, especially those related to mitochond...
Guardat en:
| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer
2026-06-01
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| Col·lecció: | Saudi Pharmaceutical Journal |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1007/s44446-026-00094-y |
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