Evaluation of Relationship of the Methylene Tetrahydrofolate Reductase Enzyme Polymorphisms with Serum Methotrexate Concentration and Toxicity in Acute Lymphoblastic Leukemia Patients Treated with High Dose Methotrexate Infusion

Background: Methotrexate (MTX) blocks Methylene Tetrahydrofolate Reductase (MTHFR) Enzyme thereby, interrupt folate metabolism, it is used in the treatment of cancer and autoimmune disorders. Aim and Objectives: The present study aimed to evaluate the relationship of the MTHFR polymorphisms wit...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Manjusha Sajith, Atmaram Pawar, Abdulrahaman A. Momin, Vibha Bafna, Sandeep Bartakke, Kannan Subramaniyan
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Krishna Vishwa Vidyapeeth (Deemed to be University), Karad 2020-07-01
Sarja:	Journal of Krishna Institute of Medical Sciences University
Aiheet:	methylene tetrahydrofolate reductase enzyme polymorphism methotrexate acute lymphoblastic leukemia
Linkit:	https://www.jkimsu.com/jkimsu-vol9no3/JKIMSU,%20Vol.%209,%20No.%203,%20July-September%202020%20Page%2027-39.pdf
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!