Differential effects of fetal bovine serum and human platelet lysate on mesenchymal stromal cell-mediated support of hematopoietic stem/progenitor cells: a functional and transcriptomic analysis
Abstract Background Umbilical cord blood (UCB) is a valuable source of hematopoietic stem and progenitor cells (HSPC) for transplantation. However, limited cell numbers require ex vivo expansion for effective treatment of adult patients. Mesenchymal stromal cell (MSC)-based co-cultures offer a suppo...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2025-11-01
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| Serie: | Stem Cell Research & Therapy |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s13287-025-04835-z |
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