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The molecular, cellular and pathophysiological roles of iRhom pseudoproteases

iRhom proteins are catalytically inactive relatives of rhomboid intramembrane proteases. There is a rapidly growing body of evidence that these pseudoenzymes have a central function in regulating inflammatory and growth factor signalling and consequent roles in many diseases. iRhom pseudoproteases h...

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Detalles Bibliográficos
Principais autores: Iqbal Dulloo, Sonia Muliyil, Matthew Freeman
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2019-03-01
Series:Open Biology
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Acceso en liña:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.190003
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