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The molecular, cellular and pathophysiological roles of iRhom pseudoproteases

iRhom proteins are catalytically inactive relatives of rhomboid intramembrane proteases. There is a rapidly growing body of evidence that these pseudoenzymes have a central function in regulating inflammatory and growth factor signalling and consequent roles in many diseases. iRhom pseudoproteases h...

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Autors principals: Iqbal Dulloo, Sonia Muliyil, Matthew Freeman
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2019-03-01
Col·lecció:Open Biology
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Accés en línia:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.190003
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