LAG3 limits regulatory T cell proliferation in α-synuclein gut-to-brain transmission model
Abstract Background Pathological α-synuclein (α-syn) can spread from the gut to the central nervous system (CNS), with CD4 + T cells playing a key role in this process. Lymphocyte activation gene 3 (LAG3) is involved in intestinal inflammation, regulates CD4 + T cell proliferation and function, and...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2025-07-01
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| Schriftenreihe: | Journal of Neuroinflammation |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s12974-025-03502-7 |
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