Extension of human GCSF serum half-life by the fusion of albumin binding domain

Abstract Granulocyte colony stimulating factor (GCSF) can decrease mortality of patients undergo chemotherapy through increasing neutrophil counts. Many strategies have been developed to improve its blood circulating time. Albumin binding domain (ABD) was genetically fused to N-terminal end of GCSF...

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Bibliografiske detaljer

Principais autores:	Fatemeh Yadavar Nikravesh, Samira Shirkhani, Elham Bayat, Yeganeh Talebkhan, Esmat Mirabzadeh, Masoumeh Sabzalinejad, Hooman Aghamirza Moghim Aliabadi, Leila Nematollahi, Yalda Hosseinzadeh Ardakani, Soroush Sardari
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2022-01-01
Serier:	Scientific Reports
Online adgang:	https://doi.org/10.1038/s41598-021-04560-6
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