Extension of human GCSF serum half-life by the fusion of albumin binding domain
Abstract Granulocyte colony stimulating factor (GCSF) can decrease mortality of patients undergo chemotherapy through increasing neutrophil counts. Many strategies have been developed to improve its blood circulating time. Albumin binding domain (ABD) was genetically fused to N-terminal end of GCSF...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2022-01-01
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| Serie: | Scientific Reports |
| Accesso online: | https://doi.org/10.1038/s41598-021-04560-6 |
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