Proton pump inhibitor alters Th17/Treg balance and induces gut dysbiosis suppressing contact hypersensitivity reaction in mice

Proton pump inhibitors (PPIs), such as omeprazole, are the most commonly prescribed drugs. Treatment with PPIs alters gut microbiota composition and reduces the production of reactive oxygen (ROS) and proinflammatory IL-1β, IL-6, and TNF-α cytokines. Here, using the T cell-dependent contact hypersen...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Anna Strzępa, Katarzyna Marcińska, Aneta Kiecka, Monika Majewska-Szczepanik, Marian Szczepanik
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-08-01
Serie:	Frontiers in Immunology
Soggetti:	proton pump inhibitors omeprazole contact hypersensitivity gut microbiota dysbiosis immunomodulation
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1390025/full
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!