The CD4+ T cell population partners with Tpex CD8+ T cells to mediate antitumor immunity in the tumor microenvironment

Abstract CD4⁺ T cells support the priming, expansion, and function of CD8⁺ T cells through dendritic cells. Precursor exhausted T cells (Tpex) maintain self-renewal and supply cytotoxic CD8⁺ T cells in the tumor microenvironment (TME), but the identity of their CD4⁺ T-cell partners remains unclear....

全面介紹

書目詳細資料

Principais autores:	Shota Takei, Satoshi Yamasaki, Ou Yamaguchi, Atsuto Mouri, Ayako Shiono, Yu Miura, Kosuke Hashimoto, Hisao Imai, Kyoichi Kaira, Yoshinobu Ichiki, Hiroyuki Nitanda, Hirozo Sakaguchi, Tomoyuki Hishida, Katsuhisa Horimoto, Hiroshi Kagamu
格式:	Artigo
語言:	Inglês
出版:	Nature Portfolio 2026-03-01
叢編:	Nature Communications
在線閱讀:	https://doi.org/10.1038/s41467-026-71161-0
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!