Cord blood T regulatory cells synergize with ruxolitinib to improve GVHD outcomes
BackgroundAdoptive therapy with umbilical cord blood (UCB) T-regulatory (Treg) cells can prevent graft vs. host disease (GVHD). We hypothesize that UCB Tregs can treat GVHD and synergize with ruxolitinib, Jak2 inhibitor, to improve outcomes.MethodsUCB Treg potency and efficacy was examined using cel...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2024-12-01
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| Colección: | Frontiers in Transplantation |
| Materias: | |
| Acceso en línea: | https://www.frontiersin.org/articles/10.3389/frtra.2024.1448650/full |
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