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Bioadhesive hybrid system of niosomes and pH sensitive in situ gel for itraconazole ocular delivery: Dual approach for efficient treatment of fungal infections

Itraconazole (ITZ) is a highly effective antifungal agent. However, its oral application is associated with systemic toxicity and poor topical use. The present study aims to improve the antifungal activity of ITZ by loading it into bioadhesive niosomes. This approach is considered to enhance the ocu...

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Autors principals: Mohamed M. Badran, Areej Alsubaie, Mounir M. Salem Bekhit, Abdullah H. Alomrani, Aliyah Almomen, Mohamed Abbas Ibrahim, Doaa Hasan Alshora
Format: Artigo
Idioma:Inglês
Publicat: Springer 2024-12-01
Col·lecció:Saudi Pharmaceutical Journal
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S1319016424002597
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