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The Combination Therapy of Dietary Galacto-Oligosaccharides With Budesonide Reduces Pulmonary Th2 Driving Mediators and Mast Cell Degranulation in a Murine Model of House Dust Mite Induced Asthma

Background: Dietary non-digestible galacto-oligosaccharides (GOS) suppress allergic responses in mice sensitized and challenged with house dust mite (HDM). Budesonide is the standard therapy for allergic asthma in humans but is not always completely effective.Aim: To compare the efficacy of budesoni...

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Principais autores: Kim A. T. Verheijden, Saskia Braber, Thea Leusink-Muis, Prescilla V. Jeurink, Suzan Thijssen, Aletta D. Kraneveld, Johan Garssen, Gert Folkerts, Linette E. M. Willemsen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-10-01
coleção:Frontiers in Immunology
Assuntos:
allergy
asthma
house dust mite
galacto-oligosaccharides
budesonide
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2018.02419/full
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