A perspective on DNA damage-induced potentiation of the pentose phosphate shunt and reductive stress in chemoresistance
Metabolic rearrangements and genome instability are two hallmarks of cancer. Recent evidence from our laboratory demonstrates that persistent DNA lesions hampering transcription may cause glucose rerouting through the pentose phosphate shunt and reductive stress. Here, we highlight the relevance of...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis Group
2020-05-01
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| Σειρά: | Molecular & Cellular Oncology |
| Θέματα: | |
| Διαθέσιμο Online: | http://dx.doi.org/10.1080/23723556.2020.1733383 |
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