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A perspective on DNA damage-induced potentiation of the pentose phosphate shunt and reductive stress in chemoresistance

Metabolic rearrangements and genome instability are two hallmarks of cancer. Recent evidence from our laboratory demonstrates that persistent DNA lesions hampering transcription may cause glucose rerouting through the pentose phosphate shunt and reductive stress. Here, we highlight the relevance of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chiara Milanese, Pier G. Mastroberardino
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis Group 2020-05-01
Cyfres:Molecular & Cellular Oncology
Pynciau:
Mynediad Ar-lein:http://dx.doi.org/10.1080/23723556.2020.1733383
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!