Atomic mutagenesis in ion channels with engineered stoichiometry

C-type inactivation of potassium channels fine-tunes the electrical signaling in excitable cells through an internal timing mechanism that is mediated by a hydrogen bond network in the channels' selectively filter. Previously, we used nonsense suppression to highlight the role of the conserved Trp43...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	John D Lueck, Adam L Mackey, Daniel T Infield, Jason D Galpin, Jing Li, Benoît Roux, Christopher A Ahern
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	eLife Sciences Publications Ltd 2016-10-01
Цуврал:	eLife
Нөхцлүүд:	atomic mutagenesis C-type inactivation noncanonical amino acids molecular dynamics intein protein ligation voltage-gated sodium channels
Онлайн хандалт:	https://elifesciences.org/articles/18976
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!