Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors?
Post-translational modifications, such as ubiquitylation, need to be tightly controlled to guarantee the accurate localization and activity of proteins. Ubiquitylation is a dynamic process primarily responsible for proteasome-mediated degradation of substrate proteins and crucial for both normal hom...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
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Frontiers Media S.A.
2022-02-01
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| Edice: | Frontiers in Cell and Developmental Biology |
| Témata: | |
| On-line přístup: | https://www.frontiersin.org/articles/10.3389/fcell.2022.854352/full |
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