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Searching for protein variants with desired properties using deep generative models

Abstract Background Protein engineering aims to improve the functional properties of existing proteins to meet people’s needs. Current deep learning-based models have captured evolutionary, functional, and biochemical features contained in amino acid sequences. However, the existing generative model...

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Bibliografiset tiedot
Päätekijät: Yan Li, Yinying Yao, Yu Xia, Mingjing Tang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2023-07-01
Sarja:BMC Bioinformatics
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Linkit:https://doi.org/10.1186/s12859-023-05415-9
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