Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding.
A causative role for single nucleotide polymorphisms (SNPs) in many genetic disorders has become evident through numerous genome-wide association studies. However, identification of these common causal variants and the molecular mechanisms underlying these associations remains a major challenge. Dif...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2012-09-01
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| Series: | PLoS Genetics |
| Acceso en liña: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002982&type=printable |
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