Deletion of Sigmar1 leads to increased arterial stiffness and altered mitochondrial respiration resulting in vascular dysfunction

Sigmar1 is a ubiquitously expressed, multifunctional protein known for its cardioprotective roles in cardiovascular diseases. While accumulating evidence indicate a critical role of Sigmar1 in cardiac biology, its physiological function in the vasculature remains unknown. In this study, we character...

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Autors principals:	Naznin Sultana Remex, Chowdhury S. Abdullah, Richa Aishwarya, Gopi K. Kolluru, James Traylor, Mohammad Alfrad Nobel Bhuiyan, Christopher G. Kevil, A. Wayne Orr, Oren Rom, Christopher B. Pattillo, Md. Shenuarin Bhuiyan
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-04-01
Col·lecció:	Frontiers in Physiology
Matèries:	SIGMAR1 physiological function vascular function mitochondria flow mediated dilatation (FMD)
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphys.2024.1386296/full
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