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Prognostic and Predictive Value of CCND1/Cyclin D1 Amplification in Breast Cancer With a Focus on Postmenopausal Patients: A Systematic Review and Meta-Analysis

BackgroundUp to 80% of breast cancers (BCa) are estrogen receptor positive and current treatments target the estrogen receptor (endocrine therapies) and/or CDK4/6 (CDK4/6 inhibitors). CCND1 encodes the protein cyclin D1, responsible for regulation of G1 to S phase transition in the cell cycle. CCND1...

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Detaylı Bibliyografya
Asıl Yazarlar: Sarah A. Jeffreys, Therese M. Becker, Sarah Khan, Patsy Soon, Hans Neubauer, Paul de Souza, Branka Powter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2022-06-01
Seri Bilgileri:Frontiers in Endocrinology
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/fendo.2022.895729/full
Etiketler: Etiketle
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