A multimodal biological margin risk index predicts recurrence after neoadjuvant immunochemotherapy in head and neck squamous cell carcinoma

BackgroundConventional classification of surgical margins is inadequate for head and neck squamous cell carcinoma (HNSCC) treated with neoadjuvant immunochemotherapy (NICT), as it fails to capture the complex biological changes in the tumor microenvironment. This study aimed to develop a novel defin...

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Autors principals:	Ning Xu, Defeng Chen, Junui Yuan, Tao Huang, Xu Zhang, Qigen Fang, Wenlu Li
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-02-01
Col·lecció:	Frontiers in Immunology
Matèries:	head and neck squamous cell carcinoma immunotherapy neoadjuvant therapy prognosis surgical margin
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1740643/full
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