Crosstalk between MSH2–MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair

The expansion of trinucleotide repeats can have detrimental effects and give rise to a range of human diseases. Here the authors report that the mismatch repair and the base excision repair machinery can operate together to promote expansion during lesion removal.

Dades bibliogràfiques

Autors principals:	Yanhao Lai, Helen Budworth, Jill M. Beaver, Nelson L. S. Chan, Zunzhen Zhang, Cynthia T. McMurray, Yuan Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2016-08-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/ncomms12465
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