The Adr1 transcription factor directs regulation of the ergosterol pathway and azole resistance in Candida albicans

ABSTRACT Transcription factors (TFs) play key roles in cellular regulation and are critical in the control of drug resistance in the fungal pathogen Candida albicans. We found that activation of the transcription factor C4_02500C_A (Adr1) conferred significant resistance against fluconazole. In Sacc...

詳細記述

書誌詳細

主要な著者:	Manjari Shrivastava, Gaëlle S. Kouyoumdjian, Eftyhios Kirbizakis, Daniel Ruiz, Manon Henry, Antony T. Vincent, Adnane Sellam, Malcolm Whiteway
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology 2023-10-01
シリーズ:	mBio
主題:	rewiring Adr1 ergosterol Candida albicans alcohol and fatty acid metabolism
オンライン･アクセス:	https://journals.asm.org/doi/10.1128/mbio.01807-23
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!