Abnormal Expression of Prolyl Oligopeptidase (POP) and Its Catalytic Products Ac-SDKP Contributes to the Ovarian Fibrosis Change in Polycystic Ovary Syndrome (PCOS) Mice

Polycystic ovary syndrome (PCOS) is an endocrine disorder and metabolic syndrome. Ovarian fibrosis pathological change in PCOS has gradually attracted people’s attention. In this study, we constructed a PCOS mouse model through the use of dehydroepiandrosterone. Sirius red staining showed that the o...

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Autors principals:	Suo Han, Shimeng Wang, Xiang Fan, Mengchi Chen, Xiaojie Wang, Yingtong Huang, Hongdan Zhang, Yinyin Ma, Jing Wang, Chunping Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2023-07-01
Col·lecció:	Biomedicines
Matèries:	polycystic ovary syndrome (PCOS) prolyl oligopeptidase (POP) N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) fibrosis TGF-β1 MMP2
Accés en línia:	https://www.mdpi.com/2227-9059/11/7/1927
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