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The renaissance of Salmonella-based cancer therapy: convergence of AI, synthetic circuits, and TME remodeling

Attenuated Salmonella has become a candidate bacterium for cancer immunotherapy, as it possesses tumor-targeting activity and is able to penetrate the hypoxic, immune-suppressive TME. However, preclinical successes were not successfully translated into early clinical trials (e.g., VNP20009) due to a...

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Detaylı Bibliyografya
Asıl Yazarlar: Zetian Zhang, Xingyu Jiang, Wenjun Huang, Xiaomeng Yang, Fan Li
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2026-04-01
Seri Bilgileri:Frontiers in Immunology
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1790215/full
Etiketler: Etiketle
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