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Microbially-derived short-chain fatty acids impact astrocyte gene expression in a sex-specific manner

Recent investigations in neuroscience implicate the role of microbial-derived metabolites, such as short-chain fatty acids (SCFAs) in brain health and disease. The SCFAs acetate, propionate and butyrate have pleiotropic effects within the nervous system. They are crucial for the maturation of the br...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Simon Spichak, Francisco Donoso, Gerard M. Moloney, Eoin Gunnigle, Jillian M. Brown, Martin Codagnone, Timothy G. Dinan, John F. Cryan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021-10-01
Schriftenreihe:Brain, Behavior, & Immunity - Health
Schlagworte:
Short-chain fatty acid
Astrocyte
Microbiome
Neuro-immunity
Glia
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2666354621001216
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